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A Phase 2, Multicenter, Open-Label, Extension Study to Evaluate the Long-Term Safety, Clinical Activity, and Pharmacokinetics of ALN-TTR02 in Patients With Familial Amyloidotic Polyneuropathy Who Have Previously Received ALN-TTR02

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Trial Profile

A Phase 2, Multicenter, Open-Label, Extension Study to Evaluate the Long-Term Safety, Clinical Activity, and Pharmacokinetics of ALN-TTR02 in Patients With Familial Amyloidotic Polyneuropathy Who Have Previously Received ALN-TTR02

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Patisiran (Primary)
  • Indications Amyloid polyneuropathy; Transthyretin-related hereditary amyloidosis
  • Focus Adverse reactions
  • Sponsors Alnylam Pharmaceuticals

    • Most Recent Events

    • 22 Apr 2021 Results assessing safety, pharmacodynamic and efficacy of patisiran from two studies including this study presented at the 73rd Annual Meeting of the American Academy of Neurology
    • 01 Sep 2020 Results describing the long term comprehensive, integrated safety data from the patisiran clinical development program presented at the ESC Congress 2020 - Annual Congress of the European Society of Cardiology
    • 30 Mar 2020 Results of integrated cardiac safety data from three studies including this study presented at the 2020 Annual Scientific Session of the American College of Cardiology and World Congress of Cardiology.

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