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A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Ranging Study Investigating the Efficacy, Safety, Pharmacokinetic and Biomarker Profiles of Dupilumab (REGN668) Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

Trial Profile

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Ranging Study Investigating the Efficacy, Safety, Pharmacokinetic and Biomarker Profiles of Dupilumab (REGN668) Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 28 Sep 2019

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At a glance

  • Drugs Dupilumab (Primary)
  • Indications Atopic dermatitis
  • Focus Therapeutic Use
  • Sponsors Regeneron Pharmaceuticals
  • Most Recent Events

    • 28 Sep 2019 Results (n=250) of sub-analysis of three studies (AD-1021; LIBERTY AD SOLO 1 and LIBERTY AD CHRONOS) assessing efficacy and safety of dupilumab in Japanese adults with moderate-to-severe atopic dermatitis, published in the British Journal of Dermatology.
    • 07 May 2019 Results assessing the impact of dupilumab on infection rates in patients with moderate-to-severe AD using pooled data from 7 randomized trials, published in the American Journal of Clinical Dermatology
    • 30 Oct 2018 Results assessing Dupilumab therapy and patient reported outcomes, published in the Journal of the American Academy of Dermatology.
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