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A Randomized, Double Blind, Placebo-Controlled, Phase 2 Study to Assess the Safety, Tolerability and Efficacy of ISIS 426115 (an Antisense Glucocorticoid Receptor Antagonist) Administered Subcutaneously Once Weekly for 6 Weeks to Patients With Type 2 Diabetes Mellitus Being Treated With Metformin

Trial Profile

A Randomized, Double Blind, Placebo-Controlled, Phase 2 Study to Assess the Safety, Tolerability and Efficacy of ISIS 426115 (an Antisense Glucocorticoid Receptor Antagonist) Administered Subcutaneously Once Weekly for 6 Weeks to Patients With Type 2 Diabetes Mellitus Being Treated With Metformin

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 22 Jul 2019

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At a glance

  • Drugs IONIS GCCRrx (Primary) ; Metformin
  • Indications Type 2 diabetes mellitus
  • Focus Pharmacodynamics
  • Sponsors Isis Pharmaceuticals
  • Most Recent Events

    • 11 May 2015 Status changed from active, no longer recruiting to completed, as reported by ClinicalTrials.gov.
    • 03 Mar 2015 Status changed from recruiting to active, no longer recruiting. as reported by ClinicalTrials.gov
    • 27 Feb 2015 Isis Pharmaceuticals expects phase II data in 2015.
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