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Phase I Study of Safety and Immunogenicity of ADU-623, a Live-attenuated Listeria Monocytogenes Strain (ΔactA/ΔinlB) Expressing the EGFRvIII-NY-ESO-1 Vaccine, in Patients With Treated and Recurrent WHO Grade III/IV Astrocytomas

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Trial Profile

Phase I Study of Safety and Immunogenicity of ADU-623, a Live-attenuated Listeria Monocytogenes Strain (ΔactA/ΔinlB) Expressing the EGFRvIII-NY-ESO-1 Vaccine, in Patients With Treated and Recurrent WHO Grade III/IV Astrocytomas

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs ADU 623 (Primary)
  • Indications Astrocytoma
  • Focus Adverse reactions; First in man

    • Most Recent Events

    • 15 Aug 2018 Status changed from active, no longer recruiting to completed.
    • 16 Jan 2018 Planned primary completion date changed from 1 Dec 2017 to 1 Jun 2018.
    • 22 Sep 2017 Status changed from recruiting to active, no longer recruiting.

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