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A Randomised, Double-Blind, Placebo-Controlled, Multicentre Phase II Study to Compare the Efficacy, Safety and Tolerability of Olaparib Versus Placebo When Given in Addition to Abiraterone Treatment in Patients With Metastatic Castrate-Resistant Prostate Cancer Who Have Received Prior Chemotherapy Containing Docetaxel

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A Randomised, Double-Blind, Placebo-Controlled, Multicentre Phase II Study to Compare the Efficacy, Safety and Tolerability of Olaparib Versus Placebo When Given in Addition to Abiraterone Treatment in Patients With Metastatic Castrate-Resistant Prostate Cancer Who Have Received Prior Chemotherapy Containing Docetaxel

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 12 Dec 2023

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At a glance

  • Drugs Olaparib (Primary) ; Abiraterone; Prednisolone; Prednisone
  • Indications Prostate cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors AstraZeneca

    • Most Recent Events

    • 10 Nov 2023 Status changed from active, no longer recruiting to completed.
    • 19 Dec 2022 Planned End Date changed from 30 Dec 2022 to 29 Dec 2023.
    • 02 Sep 2022 Results of a prespecified exploratory analysis assessed the HRQOL published in the Lancet Oncology

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