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A Phase 3 Randomized, Double-masked, Controlled Trial to Establish the Safety and Efficacy of Intravitreous Administration of Fovista (Anti PDGF-B Pegylated Aptamer) Administered in Combination With Lucentis Compared to Lucentis Monotherapy in Subjects With Subfoveal Neovascular Age-related Macular Degeneration

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A Phase 3 Randomized, Double-masked, Controlled Trial to Establish the Safety and Efficacy of Intravitreous Administration of Fovista (Anti PDGF-B Pegylated Aptamer) Administered in Combination With Lucentis Compared to Lucentis Monotherapy in Subjects With Subfoveal Neovascular Age-related Macular Degeneration

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 10 Jul 2019

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At a glance

  • Drugs Pegpleranib (Primary) ; Ranibizumab
  • Indications Choroidal neovascularisation; Wet age-related macular degeneration
  • Focus Registrational; Therapeutic Use
  • Sponsors IVERIC bio

    • Most Recent Events

    • 19 Dec 2016 Status changed from active, no longer recruiting to discontinued.
    • 12 Dec 2016 Results of a pooled analysis from OPH1002 and OPH1003 trials published in an OphthoTech Corporation Media Release
    • 12 Dec 2016 According to a Novartis media release, data from this and another (OPH1003) studies, including secondary and exploratory efficacy endpoints, will be presented at a future medical meeting.

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