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A Randomized, Multicenter, Open-Label, Phase 3 Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor PCI-32765 (Ibrutinib) Versus Rituximab in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Trial Profile

A Randomized, Multicenter, Open-Label, Phase 3 Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor PCI-32765 (Ibrutinib) Versus Rituximab in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 31 Jul 2018

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At a glance

  • Drugs Ibrutinib (Primary) ; Rituximab
  • Indications Chronic lymphocytic leukaemia; Lymphoma
  • Focus Registrational; Therapeutic Use
  • Acronyms BRILLIANCE
  • Sponsors Janssen; Janssen Research & Development
  • Most Recent Events

    • 01 Feb 2018 Status changed from active, no longer recruiting to completed.
    • 05 Jan 2017 Planned End Date changed from 1 Feb 2017 to 1 Jun 2017.
    • 22 Jan 2016 Status changed from recruiting to active, no longer recruiting, as reported by ClinicalTrials.gov.
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