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A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Safety and Efficacy of GS-6624, a Monoclonal Antibody Against Lysyl Oxidase Like 2 (LOXL2) in Subjects With Primary Sclerosing Cholangitis (PSC)

Trial Profile

A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Safety and Efficacy of GS-6624, a Monoclonal Antibody Against Lysyl Oxidase Like 2 (LOXL2) in Subjects With Primary Sclerosing Cholangitis (PSC)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 23 Oct 2019

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At a glance

  • Drugs Simtuzumab (Primary)
  • Indications Hepatic fibrosis; Primary sclerosing cholangitis
  • Focus Therapeutic Use
  • Sponsors Gilead Sciences
  • Most Recent Events

    • 31 Aug 2018 Biomarkers information updated
    • 28 Aug 2018 Results published in the Hepatology
    • 14 Apr 2018 Results of utility of serum gamma-glutamyl transferase for prediction of disease progression presented at The International Liver Congress 2018.
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