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A Phase I, Open-label, Multi-arm, Multi-centre, Multi-dose, Dose Escalation Study of LTX-315 as Monotherapy or in Combination With Either Ipilimumab or Pembrolizumab in Patients With Transdermally Accessible Tumours

Trial Profile

A Phase I, Open-label, Multi-arm, Multi-centre, Multi-dose, Dose Escalation Study of LTX-315 as Monotherapy or in Combination With Either Ipilimumab or Pembrolizumab in Patients With Transdermally Accessible Tumours

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 11 Apr 2019

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At a glance

  • Drugs Ipilimumab (Primary) ; Pembrolizumab (Primary) ; Ruxotemitide (Primary)
  • Indications Advanced breast cancer; Cancer; Head and neck cancer; Lymphoma; Malignant melanoma; Sarcoma; Solid tumours; Triple negative breast cancer
  • Focus Adverse reactions
  • Sponsors Lytix Biopharma

Most Recent Events

  • 03 Apr 2019 Results (n=27) assessing safety and efficacy of LTX-315 in patients with advanced melanoma presented at the 110th Annual Meeting of the American Association for Cancer Research
  • 03 Apr 2019 Results (n=27) from advanced sarcoma cohort were presented at the 110th Annual Meeting of the American Association for Cancer Research.
  • 21 Nov 2018 Results presented in the Lytix Biopharma media release.

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