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A Phase 1/2 Unblinded Trial of Carboxyamidotriazole Orotate (CTO) Alone or in Combination With Lomustine for Bevacizumab-Naive Adult Patients With Recurrent Malignant Glioma

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Trial Profile

A Phase 1/2 Unblinded Trial of Carboxyamidotriazole Orotate (CTO) Alone or in Combination With Lomustine for Bevacizumab-Naive Adult Patients With Recurrent Malignant Glioma

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Carboxyamidotriazole orotate (Primary) ; Lomustine
  • Indications Glioma
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 14 Jun 2016 Status changed from suspended to discontinued due to funding issues.
    • 02 Jun 2015 Interim results (n=9) presented at the 51st Annual Meeting of the American Society of Clinical Oncology.
    • 18 May 2015 Status changed from recruiting to suspended as reported by ClinicalTrials.gov.

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