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A Phase Ib Study of the Safety and Pharmacology of Atezolizumab Administered With Cobimetinib in Patients With Locally Advanced or Metastatic Solid Tumors

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Trial Profile

A Phase Ib Study of the Safety and Pharmacology of Atezolizumab Administered With Cobimetinib in Patients With Locally Advanced or Metastatic Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 19 Dec 2019

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At a glance

  • Drugs Atezolizumab (Primary) ; Cobimetinib (Primary)
  • Indications Advanced breast cancer; Colorectal cancer; Malignant melanoma; Non-small cell lung cancer; Ovarian cancer; Solid tumours; Thyroid cancer
  • Focus Adverse reactions
  • Sponsors Genentech; Roche

    • Most Recent Events

    • 16 Dec 2019 Status changed from active, no longer recruiting to completed.
    • 25 Sep 2019 Planned primary completion date changed from 1 Sep 2019 to 30 Sep 2019.
    • 27 Mar 2019 Results (n=150 data cut off 4 Sep 2017) assessing safety and clinical activity of combining cobimetinib and atezolizumab, in patients with solid tumors published in the Annals of Oncology.

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