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The Safety and Efficacy of Carfilzomib -a Novel Proteasome Inhibitor- for the Prevention of Acute Graft Versus Host Disease

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Trial Profile

The Safety and Efficacy of Carfilzomib -a Novel Proteasome Inhibitor- for the Prevention of Acute Graft Versus Host Disease

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 07 Sep 2020

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At a glance

  • Drugs Carfilzomib (Primary) ; Ciclosporin; Methotrexate
  • Indications Acute myeloid leukaemia; Graft-versus-host disease; Myelodysplastic syndromes
  • Focus Therapeutic Use

    • Most Recent Events

    • 02 Sep 2020 Results published in the Bone Marrow Transplantation.
    • 12 Dec 2017 Primary endpoint (Incidence of acute graft-versus host disease) has been met as per the results presented at the 59th Annual Meeting and Exposition of the American Society of Hematology
    • 12 Dec 2017 Results assessing safety and efficacy presented at the 59th Annual Meeting and Exposition of the American Society of Hematology

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