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Retrospective Study Based on Somatic Mutations, Genetic Polymorphisms and Metabolomics Related to Individual Variations of Drug Effect and Adverse Drug Reaction of EGFR-TKIs,Gefitinib and Erlotinib in Non-small Cell Lung Cancer Treatment

Trial Profile

Retrospective Study Based on Somatic Mutations, Genetic Polymorphisms and Metabolomics Related to Individual Variations of Drug Effect and Adverse Drug Reaction of EGFR-TKIs,Gefitinib and Erlotinib in Non-small Cell Lung Cancer Treatment

Status: Recruiting
Phase of Trial: Phase IV

Latest Information Update: 31 May 2020

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At a glance

  • Drugs Erlotinib (Primary) ; Gefitinib (Primary)
  • Indications Non-small cell lung cancer
  • Focus Pharmacogenomic; Therapeutic Use
  • Most Recent Events

    • 31 May 2020 Results presented at the 56th Annual Meeting of the American Society of Clinical Oncology
    • 31 May 2020 Results (n=172) correlation between FOXO3 and gefitinib-induced hepatotoxicity in patients with advanced non-small cell lung cancer, presented at the 56th Annual Meeting of the American Society of Clinical Oncology
    • 28 Aug 2019 Planned End Date changed from 1 Oct 2018 to 1 Dec 2021.
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