Trial Profile

A Phase 1b/2 Randomised Placebo Controlled Trial of Fulvestrant +/- AZD5363 in Postmenopausal Women With Advanced Breast Cancer Previously Treated With a Third Generation Aromatase Inhibitor

Status: Active, no longer recruiting

Phase of Trial: Phase I/II

Latest Information Update: 10 Dec 2025

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At a glance

Drugs Capivasertib (Primary) ; Fulvestrant
Indications Advanced breast cancer; HER2 negative breast cancer
Focus Adverse reactions; Therapeutic Use
Acronyms FAKTION

Most Recent Events

26 Nov 2025 Planned End Date changed from 1 Dec 2023 to 31 Dec 2025.
05 Aug 2022 Planned End Date changed from 1 Dec 2021 to 1 Dec 2023.
07 Jun 2022 Results of updated analysis from FAKTION trial presented at the 58th Annual Meeting of the American Society of Clinical Oncology

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