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A Phase 1/2a Open-Label Study to Determine the Safety and Tolerability of ALRN-6924 Alone or in Combination in Patients With Advanced Solid Tumors or Lymphomas Expressing Wild-Type p53 Protein

Trial Profile

A Phase 1/2a Open-Label Study to Determine the Safety and Tolerability of ALRN-6924 Alone or in Combination in Patients With Advanced Solid Tumors or Lymphomas Expressing Wild-Type p53 Protein

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 24 Jan 2025

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At a glance

  • Drugs ALRN 6924 (Primary) ; Palbociclib (Primary)
  • Indications Colorectal cancer; Haematological malignancies; Liposarcoma; Merkel cell carcinoma; Peripheral T-cell lymphoma; Sarcoma; Solid tumours
  • Focus Adverse reactions; First in man; Proof of concept; Therapeutic Use
  • Acronyms All-comers
  • Sponsors Aileron Therapeutics; Rein Therapeutics

Most Recent Events

  • 10 Jan 2025 According to Rein Therapeutics media release, Aileron Therapeutics announces rebranding to Rein Therapeutics
  • 22 Jul 2021 Results published in the Clinical Cancer Research
  • 13 Jul 2020 Status changed from active, no longer recruiting to completed.

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