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A Randomized, Double Blind, Placebo-Controlled, Dose Titration, Phase 2 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 494372 Administered Subcutaneously to Patients With High Lipoprotein(a)

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Trial Profile

A Randomized, Double Blind, Placebo-Controlled, Dose Titration, Phase 2 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 494372 Administered Subcutaneously to Patients With High Lipoprotein(a)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs ISIS APOARx (Primary)
  • Indications Cardiovascular disorders; Hyperlipoproteinaemia
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use
  • Sponsors Ionis Pharmaceuticals; Isis Pharmaceuticals

    • Most Recent Events

    • 22 Sep 2016 Results of this and other dose ranging trial published in an Akcea Therapeutics media release..
    • 22 Sep 2016 According to an Akcea Therapeutics media release, data from this study were published in The Lancet.
    • 21 Sep 2016 Results published in the Lancet

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