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Phase 1/2 Open-Label, Multiple-dose, Dose-escalation Study to Evaluate the Safety and Tolerability of IMO-8400 in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia.

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Trial Profile

Phase 1/2 Open-Label, Multiple-dose, Dose-escalation Study to Evaluate the Safety and Tolerability of IMO-8400 in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia.

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 13 Apr 2023

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At a glance

  • Drugs Bazlitoran (Primary)
  • Indications Waldenstrom's macroglobulinaemia
  • Focus Adverse reactions
  • Sponsors Aceragen; Idera Pharmaceuticals
  • Most Recent Events

    • 28 Aug 2019 Status changed from suspended to discontinued.
    • 28 Oct 2016 According to an Idera Pharmaceuticals media release, this trial has been suspended due to prioritization of the clinical development plans for IMO-2125, assessment showing level of clinical activity seen in the WM trial does not support monotherapy and the Companys commercial assessment of IMO-8400
    • 28 Oct 2016 Status changed from active, no longer recruiting to suspended, as reported by an Idera Pharmaceuticals media release.
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