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A Phase 1b, Open Label, Dose Escalation Study To Evaluate Safety, Pharmacokinetics And Pharmacodynamics Of Axitinib (Ag-013736) In Combination With Crizotinib (Pf-02341066) In Patients With Advanced Solid Tumors

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Trial Profile

A Phase 1b, Open Label, Dose Escalation Study To Evaluate Safety, Pharmacokinetics And Pharmacodynamics Of Axitinib (Ag-013736) In Combination With Crizotinib (Pf-02341066) In Patients With Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Axitinib (Primary) ; Crizotinib (Primary)
  • Indications Adenocarcinoma; Adrenal cancer; Advanced breast cancer; Bladder cancer; Carcinoma; Colorectal cancer; Head and neck cancer; Liver cancer; Lung cancer; Non-small cell lung cancer; Pancreatic cancer; Renal cell carcinoma; Solid tumours
  • Focus Adverse reactions
  • Sponsors Pfizer
  • Most Recent Events

    • 15 Nov 2019 Status changed from active, no longer recruiting to completed.
    • 20 Jun 2019 Planned End Date changed from 31 Jul 2018 to 30 Aug 2019.
    • 06 Jun 2017 Results (n=37; as of Aug 5, 2016), presented at the 53rd Annual Meeting of the American Society of Clinical Oncology
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