Trial Profile
A Double-Blind, Doubly-Randomized, Placebo-Controlled Study of Intranasal Esketamine in an Adaptive Treatment Protocol to Assess Safety and Efficacy in Treatment-Resistant Depression (SYNAPSE)
Status:
Completed
Phase of Trial:
Phase II
Latest Information Update: 28 Mar 2022
Price :
$35
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At a glance
- Drugs Esketamine (Primary)
- Indications Major depressive disorder
- Focus Therapeutic Use
- Acronyms SYNAPSE
- Sponsors Janssen Research & Development
- 28 Dec 2017 Primary endpoint has been met. (Change from baseline to the 1-week endpoint in Montgomery Asberg Depression Rating Scale (MADRS) total score), according to a Janssen media release.
- 28 Dec 2017 Results published in a Janssen media release.
- 27 Dec 2017 Results assessing efficacy, safety and dose response of intranasal esketamine, published in the JAMA Psychiatry.