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A Randomized Phase 3 Open Label Study of Nivolumab Versus Bevacizumab and Multiple Phase 1 Safety Cohorts of Nivolumab or Nivolumab in Combination With Ipilimumab Across Different Lines of Glioblastoma

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Trial Profile

A Randomized Phase 3 Open Label Study of Nivolumab Versus Bevacizumab and Multiple Phase 1 Safety Cohorts of Nivolumab or Nivolumab in Combination With Ipilimumab Across Different Lines of Glioblastoma

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 11 Apr 2024

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At a glance

  • Drugs Ipilimumab (Primary) ; Nivolumab (Primary) ; Bevacizumab
  • Indications Glioblastoma
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms CheckMate 143
  • Sponsors Bristol-Myers Squibb
  • Most Recent Events

    • 10 Apr 2024 This trial has been completed in Belgium, according to European Clinical Trials Database record.
    • 13 Sep 2023 Planned End Date changed from 11 Sep 2023 to 8 Apr 2024.
    • 13 Jun 2023 Planned End Date changed from 3 Jan 2023 to 11 Sep 2023.
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