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A Multicenter, Randomized, Double-blind, Parallel Group Study of Sirukumab Monotherapy Compared With HUMIRA Monotherapy Administered Subcutaneously, in Subjects With Active Rheumatoid Arthritis

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Trial Profile

A Multicenter, Randomized, Double-blind, Parallel Group Study of Sirukumab Monotherapy Compared With HUMIRA Monotherapy Administered Subcutaneously, in Subjects With Active Rheumatoid Arthritis

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 06 Sep 2023

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At a glance

  • Drugs Sirukumab (Primary) ; Adalimumab
  • Indications Rheumatoid arthritis
  • Focus Registrational; Therapeutic Use
  • Acronyms SIRROUND-H
  • Sponsors Janssen Research & Development; Janssen-Cilag

    • Most Recent Events

    • 20 Jul 2021 Results of meta-analysis from ADACTA, MONARCH and SIRROUND-H; evaluating efficacy and tolerability of tocilizumab, sarilumab, and sirukumab as monotherapy were assessed and compared with those of adalimumab in patients with rheumatoid arthritis, published in the International Journal of Clinical Pharmacology and Therapeutics
    • 24 Oct 2018 Results presented at the 82nd American College of Rheumatology and the 52nd Association of Rheumatology Health Professionals Annual Scientific Meeting
    • 26 Feb 2018 Results published in the Annals of the Rheumatic Diseases.

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