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A Phase II, Open-label Study of Efficacy and Safety of the Selective Inhibitor of Nuclear Export/SINE Compound KPT-330 (Selinexor) in Patients With Advanced Gynaecologic Malignancies

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Trial Profile

A Phase II, Open-label Study of Efficacy and Safety of the Selective Inhibitor of Nuclear Export/SINE Compound KPT-330 (Selinexor) in Patients With Advanced Gynaecologic Malignancies

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 30 Jan 2023

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At a glance

  • Drugs Selinexor (Primary)
  • Indications Adenocarcinoma; Advanced breast cancer; Carcinoma; Cervical cancer; Endometrial cancer; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Therapeutic Use
  • Acronyms SIGN
  • Sponsors Karyopharm Therapeutics
  • Most Recent Events

    • 07 Dec 2019 Results published in the Gynecologic Oncology
    • 31 Mar 2017 Status changed from active, no longer recruiting to completed.
    • 11 Oct 2016 Results assessing the efficacy and safety of selinexor in patients with metastatic ovarian, cervical & endometrial cancers presented at the 41st European Society for Medical Oncology Congress.

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