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Phase 1 Study in Subjects With Tumours Requiring Arginine to Assess ADI-PEG 20 With Pemetrexed and Cisplatin (ADIPemCis) (TRAP Study)

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Trial Profile

Phase 1 Study in Subjects With Tumours Requiring Arginine to Assess ADI-PEG 20 With Pemetrexed and Cisplatin (ADIPemCis) (TRAP Study)

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Cisplatin (Primary) ; Pegargiminase (Primary) ; Pemetrexed (Primary) ; Folic acid
  • Indications Glioma; Liver cancer; Malignant-mesothelioma; Non-small cell lung cancer; Uveal melanoma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms TRAP
  • Sponsors Polaris Pharmaceuticals

    • Most Recent Events

    • 03 Mar 2020 Status changed from active, no longer recruiting to discontinued.
    • 04 Jun 2019 Results (n=21) assessing dose-expansion study in patients with argininosuccinate syntherase 1 deficinent non-small cell lung cancer presented at the 55th Annual Meeting of the American Society of Clinical Oncology
    • 18 Mar 2019 Planned End Date changed from 1 Feb 2019 to 1 May 2020.

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