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A Randomized, Placebo-Controlled, Double-Blind, Phase 3 Study Evaluating Safety and Efficacy of the Addition of Veliparib Plus Carboplatin Versus the Addition of Carboplatin to Standard Neoadjuvant Chemotherapy Versus Standard Neoadjuvant Chemotherapy in Subjects With Early Stage Triple Negative Breast Cancer (TNBC)

Trial Profile

A Randomized, Placebo-Controlled, Double-Blind, Phase 3 Study Evaluating Safety and Efficacy of the Addition of Veliparib Plus Carboplatin Versus the Addition of Carboplatin to Standard Neoadjuvant Chemotherapy Versus Standard Neoadjuvant Chemotherapy in Subjects With Early Stage Triple Negative Breast Cancer (TNBC)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 29 Apr 2021

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At a glance

  • Drugs Veliparib (Primary) ; Carboplatin; Cyclophosphamide; Doxorubicin; Paclitaxel
  • Indications Early breast cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms BrighTNess
  • Sponsors AbbVie
  • Most Recent Events

    • 15 Jan 2021 Status changed from active, no longer recruiting to completed.
    • 05 Dec 2020 This trial has been completed in Germany, according to European Clinical Trials Database record.
    • 04 Jun 2019 Results of an analysis using immunophenotype and proliferation to predict for response to neoadjuvant chemotherapy in triple negative breast cancer patients, were presented at the 55th Annual Meeting of the American Society of Clinical Oncology.
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