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A single arm, open-label, phase 2 study to assess the efficacy and safety of lucitanib given orally as a single agent to patients with advanced/metastatic lung cancer and FGF, VEGF, or PDGF related genetic alterations

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Trial Profile

A single arm, open-label, phase 2 study to assess the efficacy and safety of lucitanib given orally as a single agent to patients with advanced/metastatic lung cancer and FGF, VEGF, or PDGF related genetic alterations

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 22 Jul 2022

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At a glance

  • Drugs Lucitanib (Primary)
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Sponsors Clovis Oncology [CEASED]; Clovis Oncology Italy; EOS S.p.A.
  • Most Recent Events

    • 18 Jul 2022 Results of a Pop PK pooled analysis from five phase 1 and 2 clinical studies: NCT01283945, NCT02053636, ISRCTN23201971, NCT02202746 and NCT02109016 published in the European Journal of Drug Metabolism and Pharmacokinetics
    • 12 Sep 2018 Status changed to discontinued.
    • 27 Jul 2016 Planned End Date changed from 1 Aug 2016 to 1 Oct 2016.

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