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A Phase 1, Open-label, Randomized, Single-dose, 3-period Cross-over, Relative Bioavailability Study to Assess Two Solid Formulations Compared to an Oral Solution of AZD3293 in Healthy Male and Non-Fertile Female Subjects

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Trial Profile

A Phase 1, Open-label, Randomized, Single-dose, 3-period Cross-over, Relative Bioavailability Study to Assess Two Solid Formulations Compared to an Oral Solution of AZD3293 in Healthy Male and Non-Fertile Female Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 23 Jan 2018

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At a glance

  • Drugs Lanabecestat (Primary)
  • Indications Alzheimer's disease
  • Focus Pharmacokinetics
  • Sponsors AstraZeneca

    • Most Recent Events

    • 01 Jan 2018 Primary endpoint (To compare the tablet formulations of AZD3293 with the oral solution of AZD3293 by evaluation of the basic pharmacokinetic parameters for each formulation) has been met as per the results published in the Clinical Pharmacology in Drug Development
    • 01 Jan 2018 Primary endpoint (The relative bioavailability of AZD3293 after administration via 2 tablet formulations compared with oral solution by assessment of the area under the plasma concentration-time curve from zero to infinity for the tablet formulations and the oral solution) has been met as per the results published in the Clinical Pharmacology in Drug Development
    • 01 Jan 2018 Results published in the Clinical Pharmacology in Drug Development

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