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Intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa: An adaptive randomized controlled non-inferiority trial

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Trial Profile

Intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa: An adaptive randomized controlled non-inferiority trial

Status: Completed
Phase of Trial: Phase II/III

Latest Information Update: 19 Feb 2018

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At a glance

  • Drugs Amphotericin B liposomal (Primary) ; Fluconazole
  • Indications Cryptococcal meningitis
  • Focus Therapeutic Use
  • Acronyms AMBITION-cm

    • Most Recent Events

    • 16 Feb 2018 Status changed from recruiting to completed.
    • 24 Oct 2017 Planned number of patients changed from 460 to 1010.
    • 27 Jan 2014 New trial record

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