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A Phase II Study to Evaluate the Efficacy, Safety, and Central Nervous System (CNS) Pharmacokinetics of the HER Family Inhibitor Dacomitinib in Progressive Brain Metastases

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Trial Profile

A Phase II Study to Evaluate the Efficacy, Safety, and Central Nervous System (CNS) Pharmacokinetics of the HER Family Inhibitor Dacomitinib in Progressive Brain Metastases

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Dacomitinib (Primary)
  • Indications Brain metastases; Breast cancer; Gastric cancer; Lung cancer; Malignant melanoma
  • Focus Therapeutic Use

    • Most Recent Events

    • 14 Jun 2016 Status changed from recruiting to discontinued due to slow enrollment.
    • 24 Apr 2014 Status changed from not yet recruiting to recruiting as reported by ClinicalTrials.gov record.
    • 03 Feb 2014 New trial record

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