Phase II Study of Redirected Autologous T Cells Engineered to Contain Anti-CD19 Attached to TCR and 4-1BB Signaling Domains in Patients With Chemotherapy Resistant or RefractoryAcute Lymphoblastic Leukemia
Latest Information Update: 31 Mar 2023
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At a glance
- Drugs Tisagenlecleucel (Primary)
- Indications B-cell lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma
- Focus Adverse reactions
- 09 Dec 2019 Results of patients with acute lymphoblastic leukemia received CTL019 as single or fractionated dosing in one of the two clinical trials: (n=7; NCT01029366 and n=42; NCT02030847) evaluating adaptive dosing schemes with optimizing safety while preserving efficacy were published in the Journal of Clinical Oncology
- 26 Oct 2018 Status changed from active, no longer recruiting to completed.
- 01 Aug 2018 Planned End Date changed from 1 Jul 2019 to 1 Dec 2019.