Trial Profile

N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecan for Patients With Relapsed or Refractory Neuroblastoma

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 24 Feb 2025

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At a glance

Drugs Eflornithine (Primary) ; Celecoxib; Cyclophosphamide; Topotecan
Indications Neuroblastoma
Focus Adverse reactions

Most Recent Events

17 Feb 2025 Status changed from active, no longer recruiting to completed.
07 Feb 2024 Planned End Date changed from 1 Dec 2023 to 30 Dec 2024.
18 Jan 2024 According to a Panbela Therapeutics media release, results from this study suggest that CPP-1X is a safe, oral treatment option that may improve response rates in heavily pretreated relapsed refractory neuroblastoma patients and are the basis for the ongoing ANBL-1821 Phase 2 trial.

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