Trial Profile

A Double-blind, Randomized, Placebo-controlled, Four-way Crossover Phase 1 Study Including an Open-label Positive Control (Moxifloxacin) to Assess the Effect of Repeated Daily Doses of 10 mg and 30 mg Macitentan on the QT/QTc Interval of the ECG in Healthy Male and Female Subjects

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 06 Feb 2025

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At a glance

Drugs Macitentan (Primary)
Indications Bacterial infections; Eisenmenger complex; Glioblastoma; Infections; Pelvic inflammatory disorders; Pulmonary arterial hypertension; Skin ulcer
Focus Adverse reactions
Sponsors Actelion Pharmaceuticals

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