A Phase 1b, Open Label, Dose Finding Study To Evaluate Safety, Pharmacokinetics And Pharmacodynamics Of Axitinib (Ag-013736) In Combination With Pembrolizumab (Mk-3475) In Patients With Advanced Renal Cell Cancer
Latest Information Update: 12 May 2022
At a glance
- Drugs Axitinib (Primary) ; Pembrolizumab (Primary)
- Indications Renal cell carcinoma
- Focus Adverse reactions
- Acronyms KEYNOTE-035
- Sponsors Pfizer
- 04 Jan 2021 Results (data cut-off date, 23rd July 2019)long-term efficacy and safety of the axitinib/pembrolizumab after 46-55 months from study initiation, published in the European Journal of Cancer
- 18 Aug 2020 Results published in the Clinical Cancer Research.
- 31 May 2020 Results assessing long-term efficacy and safety data of the combination AXI/pembro from the Phase 1 trial, with almost 5 years of follow-up, presented at the 56th Annual Meeting of the American Society of Clinical Oncology.