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NANT 2011- 01: Randomized Phase II Pick the Winner Study of 131I-MIBG, 131I-MIBG With Vincristine and Irinotecan, or 131I-MIBG With Vorinostat for Resistant/Relapsed Neuroblastoma

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NANT 2011- 01: Randomized Phase II Pick the Winner Study of 131I-MIBG, 131I-MIBG With Vincristine and Irinotecan, or 131I-MIBG With Vorinostat for Resistant/Relapsed Neuroblastoma

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Apr 2023

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At a glance

  • Drugs Iobenguane (Primary) ; Cefixime; Irinotecan; Vincristine; Vorinostat
  • Indications Neuroblastoma
  • Focus Therapeutic Use
  • Acronyms NANT2011-01

    • Most Recent Events

    • 01 Apr 2023 Results asseesing Peripheral blood biomarkers relevant to radiation exposure demonstrate significant modulation after 131I-MIBG and concomitant radiation sensitizers affect extent of modulation, published in the International Journal of Radiation Oncology, Biology, Physics
    • 07 Jun 2022 Results presented at the 58th Annual Meeting of the American Society of Clinical Oncology
    • 07 Jun 2022 Results (n=99) evaluating marker association with treatment arm, clinical response using NANT response criteria, toxicity, and whole-body radiation dose,presented at the 58th Annual Meeting of the American Society of Clinical Oncology.

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