Trial Profile

A Phase 1b Study of Abemaciclib in Combination With Therapies for Patients With Metastatic Breast Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 03 Feb 2026

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At a glance

Drugs Abemaciclib (Primary) ; Anastrozole; Everolimus; Exemestane; Fulvestrant; Letrozole; Loperamide; Pertuzumab; Samotolisib; Tamoxifen; Trastuzumab
Indications Advanced breast cancer; HER2 negative breast cancer; HER2 positive breast cancer
Focus Adverse reactions
Sponsors Eli Lilly and Company

Most Recent Events

26 Jan 2026 Planned End Date changed from 1 Dec 2025 to 1 Dec 2026.
20 Apr 2025 Planned End Date changed from 1 Dec 2024 to 1 Dec 2025.
28 Aug 2024 Planned End Date changed from 31 Dec 2024 to 1 Dec 2024.

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