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Open-Label, Multicenter, Multiple Dose Study of Safety, Tolerability, Pharmacokinetics, Efficacy Markers, and Opioid Receptor Availability of Subcutaneous Injections of Depot Buprenorphine in Treatment Seeking Opioid-Dependent Subjects

Trial Profile

Open-Label, Multicenter, Multiple Dose Study of Safety, Tolerability, Pharmacokinetics, Efficacy Markers, and Opioid Receptor Availability of Subcutaneous Injections of Depot Buprenorphine in Treatment Seeking Opioid-Dependent Subjects

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 22 Feb 2019

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At a glance

  • Drugs Buprenorphine (Primary) ; Buprenorphine (Primary)
  • Indications Opioid abuse
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Reckitt Benckiser
  • Most Recent Events

    • 22 Feb 2019 Results assessing the effects of a monthly buprenorphine depot subcutaneous injection on QT interval during treatment for opioid use disorder in 1114 subjects pooled from 5 studies (RB-US13-0001, RB-US10-0011, RB-US11-0020, RB-US12-0005, RB-US13-0006) published in the Clinical Pharmacology and Therapeutics
    • 12 Mar 2016 Results (n=89) presented at the 117th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics
    • 19 Oct 2015 Results published in the Journal of Clinical Pharmacology
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