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Phase 3 Open-Label Crossover Pharmacodynamic Study to Evaluate the Acid-inhibitory Effect of TAK-438 20 mg With Esomeprazole 20 mg or Rabeprazole Sodium 10 mg in Healthy Adult Male Subjects

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Trial Profile

Phase 3 Open-Label Crossover Pharmacodynamic Study to Evaluate the Acid-inhibitory Effect of TAK-438 20 mg With Esomeprazole 20 mg or Rabeprazole Sodium 10 mg in Healthy Adult Male Subjects

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Vonoprazan (Primary) ; Esomeprazole; Rabeprazole
  • Indications Dyspepsia; Gastro-oesophageal reflux; Helicobacter infections; NSAID-induced ulcer; Peptic ulcer; Reflux oesophagitis
  • Focus Pharmacodynamics; Registrational
  • Sponsors Takeda

    • Most Recent Events

    • 12 Jul 2015 Results published in the Alimentary Pharmacology and Therapeutics.
    • 07 May 2014 Status changed from not yet recruiting to completed as reported by ClinicalTrials.gov.
    • 14 Feb 2014 New trial record

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