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DETECT IV - A Multicenter Single Arm Phase II Study to Investigate the Clinical Efficacy of Everolimus in Combination With Endocrine Therapy in Postmenopausal Patients With Hormone-receptor Positive, HER2-negative Metastatic Breast Cancer and Persisting HER2-negative Circulating Tumor Cells

Trial Profile

DETECT IV - A Multicenter Single Arm Phase II Study to Investigate the Clinical Efficacy of Everolimus in Combination With Endocrine Therapy in Postmenopausal Patients With Hormone-receptor Positive, HER2-negative Metastatic Breast Cancer and Persisting HER2-negative Circulating Tumor Cells

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 30 Oct 2019

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At a glance

  • Drugs Eribulin (Primary) ; Everolimus (Primary) ; Ribociclib (Primary)
  • Indications Advanced breast cancer
  • Focus Therapeutic Use
  • Acronyms DETECT-IV
  • Most Recent Events

    • 30 Oct 2019 Ribociclib as a primary drug is added in trial.
    • 23 Oct 2019 Planned End Date changed from 1 Dec 2020 to 1 Dec 2022.
    • 23 Oct 2019 Planned number of patients changed from 520 to 300.
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