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A Phase III, Long Term, Open Label, Follow on Study of Microsomal Triglyceride Transfer Protein (MTP) Inhibitor 'Lomitapide' (LOMITAPIDE) in Patients With Homozygous Familial Hypercholesterolemia

Trial Profile

A Phase III, Long Term, Open Label, Follow on Study of Microsomal Triglyceride Transfer Protein (MTP) Inhibitor 'Lomitapide' (LOMITAPIDE) in Patients With Homozygous Familial Hypercholesterolemia

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 06 Feb 2023

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At a glance

  • Drugs Lomitapide (Primary)
  • Indications Hypercholesterolaemia
  • Focus Therapeutic Use
  • Sponsors Aegerion Pharmaceuticals

Most Recent Events

  • 01 Feb 2023 Results assessing long-term hepatic safety of lomitapide from phase III clinical studies and extension study: NCT00730236, NCT00943306 and NCT02135705 published in the Liver International
  • 18 Jul 2017 Results of an open-label extension study assessing additional long-term efficacy and safety of lomitapide along with results of an exploratory post hoc analysis assessing the potential metabolic consequences of hepatic fat accumulation, published in the Circulation Journal as a research letter.
  • 18 Mar 2015 Status changed from active, no longer recruiting to completed, according to to ClinicalTrials.gov record.

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