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Open Label Randomized Bioequivalence Study to Evaluate the Pharmacokinetic and Safety Profile of Bevacizumab Biosimilar (BEVZ92) vs Bevacizumab (AVASTIN®), Both With FOLFOX or FOLFIRI, in First-line Treatment for mCRC Patients

Trial Profile

Open Label Randomized Bioequivalence Study to Evaluate the Pharmacokinetic and Safety Profile of Bevacizumab Biosimilar (BEVZ92) vs Bevacizumab (AVASTIN®), Both With FOLFOX or FOLFIRI, in First-line Treatment for mCRC Patients

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 24 Jul 2019

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At a glance

  • Drugs Bevacizumab (Primary) ; Fluorouracil; Folinic acid; Irinotecan; Oxaliplatin
  • Indications Colorectal cancer
  • Focus Pharmacokinetics
  • Sponsors mAbxience
  • Most Recent Events

    • 14 Feb 2018 Status changed from active, no longer recruiting to completed.
    • 18 Sep 2017 Planned End Date changed from 1 Jun 2017 to 1 Dec 2017.
    • 02 Jun 2017 Results presented at the 53rd Annual Meeting of the American Society of Clinical Oncology.
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