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A Prospective, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group, 12-week Study to Evaluate the Safety and Tolerability of Macitentan in Subjects With Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH) Due to Left Ventricular Dysfunction

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Trial Profile

A Prospective, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group, 12-week Study to Evaluate the Safety and Tolerability of Macitentan in Subjects With Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH) Due to Left Ventricular Dysfunction

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 28 May 2019

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At a glance

  • Drugs Macitentan (Primary)
  • Indications Pulmonary hypertension
  • Focus Adverse reactions
  • Acronyms MELODY-1
  • Sponsors Actelion Pharmaceuticals

    • Most Recent Events

    • 31 Aug 2018 Biomarkers information updated
    • 01 Feb 2018 Results published in the European Respiratory Journal
    • 21 Nov 2015 Status changed from active, no longer recruiting to completed as per European Clinical Trials Database.
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