Trial Profile

A Randomized, Open-label, Phase 2 Trial of Ponatinib in Patients With Resistant Chronic Phase Chronic Myeloid Leukemia to Characterize the Efficacy and Safety of a Range of Doses

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 18 May 2026

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At a glance

Drugs Ponatinib (Primary)
Indications Chronic myeloid leukaemia
Focus Registrational; Therapeutic Use
Acronyms OPTIC
Sponsors ARIAD Pharmaceuticals; Takeda Development Center Americas; Takeda Pharma

Most Recent Events

17 Mar 2026 Actual primary completion date changed from 14 Apr 2020 to 29 Apr 2020.
01 May 2025 Status changed from active, no longer recruiting to completed.
08 Jan 2025 Planned End Date changed from 31 Dec 2024 to 31 Mar 2025.

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