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A Randomized, Phase III Study of Intra-anal Imiquimod 2.5% vs. Topical 5-fluorouracil 5% vs. Observation for the Treatment of High-grade Anal Squamous Intraepithelial Lesions in HIV-infected Men and Women

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Trial Profile

A Randomized, Phase III Study of Intra-anal Imiquimod 2.5% vs. Topical 5-fluorouracil 5% vs. Observation for the Treatment of High-grade Anal Squamous Intraepithelial Lesions in HIV-infected Men and Women

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 27 May 2025

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At a glance

  • Drugs Imiquimod (Primary) ; Fluorouracil; Fluorouracil
  • Indications Anal intraepithelial neoplasia
  • Focus Therapeutic Use

Most Recent Events

  • 20 May 2025 Status changed from active, no longer recruiting to completed.
  • 16 Oct 2024 Planned End Date changed from 21 May 2024 to 25 Apr 2025.
  • 16 Oct 2024 Status changed from completed to active, no longer recruiting.

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