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A Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Explore the Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy Adult Male Subjects

Trial Profile

A Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Explore the Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy Adult Male Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 21 Oct 2019

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At a glance

  • Drugs Oliceridine (Primary) ; Morphine
  • Indications Pain
  • Focus Proof of concept; Therapeutic Use
  • Sponsors Trevena
  • Most Recent Events

    • 21 Oct 2019 According to a Trevena media release, data from this study was presented at national conference for the American Society of Anesthesiologists, held at the Orange County Convention Center in Orlando, Florida, October 19-23
    • 07 Feb 2018 Results of pooled data from six phase 1 and phase 2 trial assessing population pharmacokinetic/pharmacodynamic (PK/PD) model of the PK and PD of oliceridine, were published in the Journal of Clinical Pharmacology.
    • 03 May 2014 Primary endpoint 'Pain-relief' has been met.
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