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A Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Explore the Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy Adult Male Subjects

Trial Profile

A Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Explore the Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy Adult Male Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 22 May 2023

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At a glance

  • Drugs Oliceridine (Primary) ; Morphine
  • Indications Pain
  • Focus Proof of concept; Therapeutic Use
  • Sponsors Trevena
  • Most Recent Events

    • 15 May 2023 According to a Trevena media release, topline data expected in 3Q 2023 from this proof of concept study supporting continued development for potential use in chronic pain.
    • 01 Sep 2020 Data were used for population pharmacokinetic-pharmacodynamic analysis from this trial published in the Anesthesiology
    • 26 Aug 2020 Results from a pooled analysis of this trial presented in a Trevena Media Release.

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