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A Phase 2, Multicenter, Randomized Study to Evaluate the Safety and Efficacy of Viagenpumatucel-L (HS-110) in Combination With Low Dose (Metronomic) Cyclophosphamide Versus Chemotherapy Alone in Patients With Non-Small Cell Lung Adenocarcinoma After Failure of Two or Three Previous Treatment Regimens for Advanced Disease

Trial Profile

A Phase 2, Multicenter, Randomized Study to Evaluate the Safety and Efficacy of Viagenpumatucel-L (HS-110) in Combination With Low Dose (Metronomic) Cyclophosphamide Versus Chemotherapy Alone in Patients With Non-Small Cell Lung Adenocarcinoma After Failure of Two or Three Previous Treatment Regimens for Advanced Disease

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Viagenpumatucel-L (Primary) ; Antineoplastics; Cyclophosphamide; Docetaxel; Erlotinib; Gemcitabine; Paclitaxel; Pemetrexed; Vinorelbine
  • Indications Adenocarcinoma; Non-small cell lung cancer
  • Focus Proof of concept; Therapeutic Use
  • Sponsors Scorpius Holdings

Most Recent Events

  • 18 Apr 2018 According to a Heat Biologics media release, interim data readout is expected in Q4 2018 and final readout in Q2 2019.
  • 07 Dec 2017 According to a Heat Biologics media release, data read-out is anticipated in the second half of 2018.
  • 21 Apr 2017 Planned End Date changed from 1 Jun 2018 to 1 Sep 2018.

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