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A multi-center, open-label, continuation trial LymphoStat-B antibody (monoclonal anti-BLyS antibody) in subjects with systemic lupus erythematosus (SLE) who completed the phase 2 protocol LBSL02

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Trial Profile

A multi-center, open-label, continuation trial LymphoStat-B antibody (monoclonal anti-BLyS antibody) in subjects with systemic lupus erythematosus (SLE) who completed the phase 2 protocol LBSL02

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 01 Jan 2024

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At a glance

  • Drugs Belimumab (Primary)
  • Indications Systemic lupus erythematosus
  • Focus Adverse reactions; Pharmacodynamics
  • Sponsors Human Genome Sciences

    • Most Recent Events

    • 15 Nov 2023 Results of post hoc analysis pooled data from the three multicenter LTE studies (112626, 112233, 112234), presented at the ACR Convergence 2023.
    • 15 Nov 2023 Results of comprehensive analysis of infections among BEL-treated patient presented at the ACR Convergence 2023
    • 03 Jun 2023 Results of post-hoc pooled analysis data from three LTE studies BLISS-52 + BLISS-76 LTE (excluding US patients from BLISS-76; Phase 3; GSK Study 112234) assessing long-term safety of belimumab, presented at the 24th Annual Congress of the European League Against Rheumatism.

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