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Phase II, Open Label, Single-arm Study to Assess Safety and Efficacy of AZD9291 in Patients With Locally Advanced/Metastatic NSCLC Whose Disease Has Progressed With Previous EGFR TKI and Whose Tumours Are EGFR and T790M Mutation Positive

Trial Profile

Phase II, Open Label, Single-arm Study to Assess Safety and Efficacy of AZD9291 in Patients With Locally Advanced/Metastatic NSCLC Whose Disease Has Progressed With Previous EGFR TKI and Whose Tumours Are EGFR and T790M Mutation Positive

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 24 Feb 2021

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At a glance

  • Drugs Osimertinib (Primary)
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms AURA2
  • Sponsors AstraZeneca
  • Most Recent Events

    • 05 Feb 2021 Planned End Date changed from 30 Dec 2020 to 31 Dec 2021.
    • 23 Dec 2020 Results of post hoc analysis from trials (FLAURA, AURA3, AURA2 and AURA) published in the Journal of Clinical Oncology
    • 24 Jan 2020 Planned End Date changed from 26 Dec 2019 to 30 Dec 2020.
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