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A Phase I/II Study of Carfilzomib in Combination With R-CHOP (CR-CHOP) for Patients With Diffuse Large B-cell Lymphoma

Trial Profile

A Phase I/II Study of Carfilzomib in Combination With R-CHOP (CR-CHOP) for Patients With Diffuse Large B-cell Lymphoma

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 30 May 2024

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At a glance

  • Drugs Aciclovir (Primary) ; Carfilzomib (Primary) ; Cyclophosphamide (Primary) ; Doxorubicin (Primary) ; Filgrastim (Primary) ; Filgrastim (Primary) ; Pegfilgrastim (Primary) ; Prednisone (Primary) ; Rituximab (Primary) ; Vincristine (Primary)
  • Indications Diffuse large B cell lymphoma
  • Focus Adverse reactions

Most Recent Events

  • 02 May 2024 Status changed from active, no longer recruiting to completed.
  • 12 Dec 2023 Results assessing the safety and efficacy of K in combination with R-CHOP (KR-CHOP) and the recommended phase 2 dose (RP2D) in all DLBCL patients, were presented at the 65th American Society of Hematology Annual Meeting and Exposition.
  • 12 Jan 2022 Planned End Date changed from 1 Dec 2021 to 1 Dec 2022.

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