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Multicenter Phase I/II Trial of Ruxolitinib in Combination With Decitabine in Patients With Accelerated Phase Myeloproliferative Neoplasm (MPN) or Post-MPN AML

Trial Profile

Multicenter Phase I/II Trial of Ruxolitinib in Combination With Decitabine in Patients With Accelerated Phase Myeloproliferative Neoplasm (MPN) or Post-MPN AML

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 16 Jun 2019

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At a glance

  • Drugs Decitabine (Primary) ; Ruxolitinib (Primary)
  • Indications Acute myeloid leukaemia; Essential thrombocythaemia; Myelodysplastic syndromes; Myelofibrosis; Myeloproliferative disorders; Polycythaemia vera
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 26 Feb 2019 Status changed from active, no longer recruiting to completed.
    • 26 Feb 2019 Status changed from active, no longer recruiting to completed.
    • 04 Dec 2018 Final results of the phase 2 combination of Ruxolitinib + Decitabine presented at the 60th Annual Meeting and Exposition of the American Society of Hematology.
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