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A Double-Blind, Active-Controlled, Long-Term Safety Extension Study of Optimized Doses of Darusentan in Subjects With Resistant Hypertension Despite Receiving Combination Therapy With Three or More Antihypertensive Drugs, Including a Diuretic, as Compared to Guanfacine (Protocol DAR-312-E) [EXTENSION OF 700013256]

Trial Profile

A Double-Blind, Active-Controlled, Long-Term Safety Extension Study of Optimized Doses of Darusentan in Subjects With Resistant Hypertension Despite Receiving Combination Therapy With Three or More Antihypertensive Drugs, Including a Diuretic, as Compared to Guanfacine (Protocol DAR-312-E) [EXTENSION OF 700013256]

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 24 Sep 2019

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At a glance

  • Drugs Darusentan (Primary) ; Guanfacine
  • Indications Resistant hypertension
  • Focus Therapeutic Use
  • Acronyms DORADO-AC-EX
  • Sponsors Gilead Sciences; Myogen
  • Most Recent Events

    • 01 Apr 2014 New source identified and integrated (EudraCT2006-003548-42).
    • 28 Mar 2014 New trial record
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